Glial Cell Modulators and Associated Anti-Inflammatory Activity: Implications in Reducing Methamphetamine Abuse-Related Behaviors in Rodents
نویسندگان
چکیده
.................................................................................................................................... xii Chapter I: INTRODUCTION ...................................................................................................... 1 Background and Significance ................................................................................................. 1 Methamphetamine abuse .................................................................................................... 1 Current treatments .............................................................................................................. 4 Methamphetamine’s Neurochemical Effects ........................................................................... 5 Monoamines ....................................................................................................................... 5 Cyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) ................................................................................................................. 7 Glial Cells...........................................................................................................................10 Importance of Glia .................................................................................................................12 Gliotransmission ................................................................................................................12 Regulation of synaptic strength by cytokines ......................................................................13 Effects of other drugs on glia..............................................................................................14
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